INBRE

Kriya Dunlap

Assistant Professor

University of Alaska Fairbanks
PO Box 757000
230 West Ridge Research Building
Fairbanks, AK 99775
Tel: 907-474-2766
 
● Biochemistry ● Nutrition
 
 
Affiliations
● INBRE
   (IDeA Network of Biomedical Research Excellence)
●  Institute of Arctic Biology (UAF)
●  Department of Biology and Wildlife (UAF)
● Affiliate faculty Department of Chemistry and Biochemistry (UAF)
● Engineering, Science and Technology Experiment Sation (ESTES)
 
Specialties
● Cell Culture
● Microscopy
● Enzyme-linked immunosorbent assay (ELISA)
● Flow Cytometry
● Canine blood sampling
● Buffy coat and plasma extraction
 
 
 
Education
B.S. 1998 Animal Science
    Cornell University, Ithaca, NY
● M.S. 2003 Biochemistry and Molecular Biology
   University of Alaska Fairbanks, AK
● Ph.D. 2007 Nutrition
   University of Alaska Fairbanks, AK
 
Research Overview
My research centers around developing health relevant research models that incorporate the nutritive properties of indigenous foods and the molecular basis by which they combat age and diet related diseases. Ongoing projects involve developing sled dogs as a sentinel and model for assessing the impacts of nutrition, exercise, and environmental stressors on biomarkers in blood and hair. My research also includes a cell model with relevance to human physiology. Currently we are investigating compounds in wild Alaska blueberries and their potential impact on pathways associated with insulin resistance; a national concern and a growing concern among Alaska Natives. Alaskan natural resources and cultural background provide valuable and exciting research avenues, which continue to shape and direct my research interests.
 
Current Research Projects
  Glucose transporter 4 expression on the plasma membrane of resting and activated white blood cells
 
Peer Reviewed Publications (in chronolgical order)

1.     Dunlap KL, Reynolds AJ, Duffy LK. (2006) Total antioxidant power in sled dogs supplemented with blueberries and the comparison of blood parameters associated with exercise. Comp Biochem Physiol A Mol Integr Physiol; 143(4): 429-34. [PMID: 16520073]

2.     Dunlap KL, Reynolds AJ, Tosini G, Kerr WW, Duffy LK. (2007) Seasonal and diurnal melatonin production in exercising sled dogs. Comp Biochem Physiol A Mol Integr Physiol; 147(4): 863-7. [PMID: 17379556]
 
3.     Dunlap KL, Reynolds AJ, Bowers PM, Duffy LK. (2007) Hair analysis in sled dogs (Canis lupus familiaris) illustrates a linkage of mercury exposure along the Yukon River with human subsistence food systems. Sci Total Environ; 385(1-3): 80-5. [PMID: 17707466]
 
4.     Dunlap KL, Reynolds AJ, Refsal KR, Kerr WW, Duffy LK. (2008) Crosslatitudinal, seasonal and diurnal comparisons in thyroid hormone concentrations in sled dogs. Am J Animal & Vet Sci; 3(4): 96-103.
 
5.     Lokken JA, Finstad GL, Dunlap KL, Duffy LK. (2009) Mercury in lichen and reindeer hair from Alaska: 2005-2007 pilot survey. Polar Record; 45(4): 368-374.
 
6.     Dunlap KL, Reynolds AJ, Gerlach SG, Loring PA, Duffy LK. (2011) Lipid profiles in subsistence fed sled dogs along the Yukon River. Polar Record Pending.
 
7.     Gustafson SJ, Dunlap KL, McGill CM, Clausen TP, Kuhn TB. (2011) A nonpolar and non-antioxidant blueberry fraction blunts NADPH oxidase activation in neuronal cells exposed to Tumor Necrosis Factor α. Journal of Nutritional Biochem
 
8.     Duffy LK, Nicholas-Figueroa L, Dunlap KL (2011) Involvement of Cytokine IL-1Ra in Regulating the Secretion of VEGF in SH-SY5Y Neuroblastoma Cells. Neuroimmunomodulation.
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