University of Alaska Anchorage
Integrated Science Building 301f
Anchorage, Alaska 99508
● Biological Sciences
(IDeA Network of Biomedical Research Excellence)
● University of Alaska Anchorage
College of Arts and Sciences
● Aquatic environmental microbiology
● Microbial ecology
● Host-microbe interactions
● B.S. 1990 Biology / Microbiology
Virginia Polytechnic Institute and State University (Va Tech)
● M.S. 1993 Biology
● Ph.D. 1998 Microbiology
Oregon State University
● Post Doctoral 2002 Wetland Biogeochemistry
University of Alaska, Anchorage
Research in my lab currently focuses on two areas of inquiry, aquatic environmental microbiology and gut microbial ecology. Specifically, my lab has focused on evaluating the source and transport mechanisms of microbial contaminants in freshwater systems in urban and rural settings, with the ultimate goal of understanding the link between source, transport, and human disease. In addition, my lab is examining the gut microbial community of arctic ground squirrels. The radical shifts in physiology experienced by arctic ground squirrels make then an excellent model with which to study the complex reciprocal interactions between the host and the gut microbiota as it relates to disease.
Current Research Projects
● The effect of hibernation stage and temperature on the gut microbial community of the arctic ground squirrel.
● Development of the gut microbial community in juvenile arctic ground squirrels.
● The response of the gut microbial community to change in arctic ground squirrel physiology across the active season: implications for the role of the gut microbiota in obesity.
1. Timothy Stevenson (current M. S., Committee Co-Chair)
2. Edda Mutter (current. Ph.D. UAF Interdisciplinary studies, Committee member)
3. Joel Gottschalk (M.S., 2011, Committee Chair)
1. Brian Quinlan (B.S. expected 2012)
Peer Reviewed Publications
1. Duddleston, K. N., P. J. Bottomley, A. J. Porter, and D. J. Arp. 2000. Effects of soil and water content on methyl bromide oxidation by the ammonia-oxidizing bacterium, Nitrosomonas europaea. Appl. Environ. Microbiol. 66:2636-2640. [ PMID: 10831449]
2. Duddleston, K. N., P. J. Bottomley, A. J. Porter, and D. J. Arp. 2000. New insights into methyl bromide cooxidation by Nitrosomonas europaea obtained from experimenting with moderately low density cell suspensions. Appl. Environ. Microbiol. 66: 2726-2731. [PMID: 10877761]
3. Hines, M. E., K. N. Duddleston, and R. P. Kiene. 2001. Carbon flow to acetate and C1 compounds in northern wetlands. Geophys. Res. Lett. 28:4251-4254.
4. Duddleston, K. N., D. J. Arp and P. J. Bottomley. 2002. Biodegradation of monohalogenated alkanes by soil NH3- oxidizing bacteria. Appl. Microbiol. Biotechnol. 59:535-539. [ PMID: 12172622]
5. Duddleston, K. N., M. A. Kinney, R. P. Kiene and M. E. Hines. 2002. Anaerobic microbial biogeochemistry in a northern bog: acetate as a dominant metabolic end product. Global Biogeochem. Cycles. 16(4):1063, doi:10.1029/2001GB001402,2002.
6. Rooney-Varga, J. N., M. W. Giewat, K. N. Duddleston, J. P. Chanton and M. E. Hines. 2007. Links between Archaea community structure, vegetation type, and methanogenic pathways in Alaskan peatlands. FEMS Microbiology Ecology. 60(2): 240-251. [PMID: 17316328]
7. Hines, M. E., K. N. Duddleston, J. N. Rooney-Varga, D. Fields and J. P. Chanton. 2008. Uncoupling of acetate degradation from methane formation in Alaskan wetlands: Connections to vegetation distribution. Global Biogeochem. Cycles. 22, GB2017, doi:10.1029/2006GB002903.
8. Schnabel, W. E., T. Wilson, R. Edwards, G. Stahnke, M. Maselko, D. C. Maddux and K.N. Duddleston. 2010. Variability, seasonality, and persistence of fecal coliform bacteria in a cold-region, urban stream. Journal of Cold Regions Engineering. 24(2):54-75.