Brian Edmonds

Assistant Professor

University of Alaska Fairbanks

Fairbanks, Alaska 99775
● Biochemistry ●  Biophysics
   (IDeA Network of Biomedical Research Excellence)
University of Alaska Fairbanks
   Chemistry & Biochemistry
   Institute of Arctic Biology
●B.S. 1981 Biological Sciences
 Stanford University
Ph.D. 1990 Physiology/Biophysics
Post Doctoral 1996 Ion Channel Biophysics
   University College, London England
Post Doctoral 1999 Synaptic Physiology
   University of Oregon
Post Doctoral2001 Synaptic Physiology
   University of California, Los Angeles
Post Doctoral 2004 X-Ray Crystallography
   University of California, Irvine
Current Research Projects
● Mechanisms of Activation and Modulation of Human Neuronal Nicotinic Receptors
Peer Reviewed Publications (in chronological order)
1.     Edmonds, B. and Colquhoun, D. (1992) Rapid decay of averaged single-channel NMDA receptor activations recorded at low agonist concentration. Proc. Roy. Soc. Lond. B 250, 279 [PMID: 1283640]
2.     Silver, R.A., Colquhoun, D., Cull-Candy, S.G. and Edmonds, B. (1996) Deactivation and desensitization of non-NMDA receptors in patches and the time course of EPSCs in rat cerebellar granule cells. J.Physiol. (Lond) 493, 167 [PMID: 8735702]
3.     Colquhoun, D., Hawkes, A.G., Merlushkin, A. and Edmonds, B. (1997) Properties of single ion channel currents elicited by a pulse of agonist concentration or voltage. Phil. Trans. R. Soc. Lond. A 355, 1743
4.     Kim, J-S., Pandya, A., Weltzin, M., Edmonds, B.W., Schulte, M.K. and Glennon, R.A. (2007) Synthesis of desformylflustrabromine and its evaluation as an a 4 b 2 and a 7 nACh receptor modulator. Bioorg. Med. Chem. Lett. 17, 4855 [PMID: 17604168]
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