INBRE | Brian Edmonds

INBRE

Alaska INBRE
PO Box 757040
202 West Ridge Research Bldg.
Fairbanks, Alaska 99775

email: inbre@alaska.edu
phone: 907.474.1527
fax: 907.474.6745

This publication was made possible by grants from the National Center for the Research Resources (5P20RR016466) and the National National Institute of General Medical Sciences (8P20GM103395-12), from the National Institutes of Health. It's contents are the sole responsibility of the authors and do not necessarily represent the official view of NCRR or NIH

Brian Edmonds

Assistant Professor

University of Alaska Fairbanks

Fairbanks, Alaska 99775

907-474-6527

bwedmonds@alaska.edu

● Biochemistry ● Biophysics

Affiliations

● INBRE

(IDeA Network of Biomedical Research Excellence)

● University of Alaska Fairbanks

Chemistry & Biochemistry

Institute of Arctic Biology

Education

●B.S. 1981 Biological Sciences

Stanford University

● Ph.D. 1990 Physiology/Biophysics

● Post Doctoral 1996 Ion Channel Biophysics

University College, London England

● Post Doctoral 1999 Synaptic Physiology

University of Oregon

● Post Doctoral2001 Synaptic Physiology

University of California, Los Angeles

● Post Doctoral 2004 X-Ray Crystallography

University of California, Irvine

Current Research Projects

● Mechanisms of Activation and Modulation of Human Neuronal Nicotinic Receptors

Publications

Peer Reviewed Publications (in chronological order)

1. Edmonds, B. and Colquhoun, D. (1992) Rapid decay of averaged single-channel NMDA receptor activations recorded at low agonist concentration. Proc. Roy. Soc. Lond. B 250, 279 [PMID: 1283640]

2. Silver, R.A., Colquhoun, D., Cull-Candy, S.G. and Edmonds, B. (1996) Deactivation and desensitization of non-NMDA receptors in patches and the time course of EPSCs in rat cerebellar granule cells. J.Physiol. (Lond) 493, 167 [PMID: 8735702]

3. Colquhoun, D., Hawkes, A.G., Merlushkin, A. and Edmonds, B. (1997) Properties of single ion channel currents elicited by a pulse of agonist concentration or voltage. Phil. Trans. R. Soc. Lond. A 355, 1743

4. Kim, J-S., Pandya, A., Weltzin, M., Edmonds, B.W., Schulte, M.K. and Glennon, R.A. (2007) Synthesis of desformylflustrabromine and its evaluation as an a 4 b 2 and a 7 nACh receptor modulator. Bioorg. Med. Chem. Lett. 17, 4855 [PMID: 17604168]